Post-irradiation angiosarcoma of the breast.

Radiation-induced second non-mammary malignancies are infrequent long term complications of the therapy. Angiosarcoma is particularly challenging to diagnose given its rare presentation (less than 1% of all malignancies of the breast) and clinical resemblance to radiation-induced skin changes [1]. Therefore, it is crucial to have a high index of suspicion in these patients. It is commonly seen in older patients, with a mean age of 68 years and a latency period of 5 or more years (range 3-25 years) [24]. We report a case of an early presentation of angiosarcoma of the breast following breast conservation surgery and radiation therapy for breast cancer.